EMF Health-effects Research
Dual effects of microwaves on single Ca(2+)-activated K+ channels in cultured kidney cells
Geletyuk VI, Kazachenko VN, Chemeris NK, Fesenko EE,
FEBS Lett 359(1):85-88, 1995
Using the patch voltage-clamp method, possible effects of millimetre microwaves (42.25 GHz) on single Ca(2+)-activated K+ channels in cultured kidney cells (Vero) were investigated. It was found that exposure to the field of non-thermal power (about 100 microW/cm2) for 20-30 min greatly modifies both the Hill coefficient and an apparent affinity of the channels for Ca2+(i). The data suggest that the field alters both cooperativity and binding characteristics of the channel activation by internal Ca2+. The effects depend on initial sensitivity of the channels to Ca2+ and the Ca2+ concentration applied.