EMF Health-effects Research

Case-control study of the association between the use of cellular and cordless telephones and malignant brain tumors diagnosed during 2000-2003

Hardell L, Carlberg M, Mild K.

Environmental Research 2005

Environmental Research 2005. doi:10.1016/j.envres.2005.04.006

We performed a case­control study on the use of cellular and cordless telephones and the risk for brain tumors diagnosed during 2000­2003. We report the results for malignant brain tumors with data from 317 cases (88%) and 692 controls (84%).

The use of analog cellular phones yielded odds ratio (OR) of 2.6 and a 95% confidence interval (CI) of 1.5­4.3, increasing to OR=3.5 and 95% CI=2.0­6.4 with a >10-year latency period. Regarding digital cellular telephones, the corresponding results were OR=1.9, 95% CI=1.3­2.7 and OR=3.6, 95% CI=1.7­7.5, respectively. Cordless telephones yielded OR=2.1, 95% CI=1.4­3.0, and with a >10-year latency period, OR=2.9, 95% CI=1.6­5.2.

The OR increased with the cumulative number of hours of use and was highest for high-grade astrocytoma. A somewhat increased risk was also found for low-grade astrocytoma and other types of malignant brain tumors, although not significantly so. In multivariate analysis, all three phone types studied showed an increased risk.

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